San Diego Union-Tribune

BIOTECH HELPED MAKE PROGRESS

- BY JOE PANETTA, MIKE GUERRA & MICHELLE MCMURRY-HEATH Panetta is president and CEO of Biocom California and lives in Carmel Valley. Guerra is president and CEO of California Life Sciences, and lives in Morgan Hill. McMurry-Heath is president and CEO of the

The COVID-19 pandemic made a simple fact painfully clear: Our world is smaller and more connected than ever before, meaning that dangerous viruses and other communicab­le diseases can travel faster and farther than at any other time in human history. The question isn’t whether a new virus or strain will threaten us. The question is when.

How will society confront such an epic challenge? Thankfully, a robust and innovative life science community is built on close collaborat­ion among companies, universiti­es, research institutes and all levels of government. It is this very community that has been at the forefront of battling the current pandemic, and it is this community that will lead the charge preparing for the next.

It is unimaginab­le to think of where we might be today without the biotech industry. A study released in April by Yale University and the Commonweal­th Fund had remarkable takeaways: Between December 2020 and March 2022, the U.S. vaccinatio­n program averted more than 2.2 million deaths and more than 17 million hospitaliz­ations and saved nearly $900 billion in associated health care costs.

And here in San Diego, biotech companies have played a critical role in the fight against COVID-19. San Diego is home to several of the leading COVID-19 test manufactur­ers, including Genalyte, Mesa Biotech and Truvian Sciences. Quidel developed the first coronaviru­s antigen test to receive emergency use authorizat­ion, and Helix worked hand-in-hand with San Diego County government to process thousands of samples from testing sites.

In January 2020, scientists used Illumina technology to determine the first genetic sequence of the virus in just a few days — the sort of feat that once took months. Meanwhile, scientists at the San Diego office of Eli Lilly and Co. led the developmen­t of the first authorized neutralizi­ng antibody therapy for COVID-19 (which the company found helped reduce the risk of hospitaliz­ation and death by up to 70 percent), and Gilead currently leverages a Ligand Pharmaceut­icals technology to administer remdesivir, an antiviral medication approved to treat COVID-19 in certain situations. What’s more, The Scripps Research Institute and La Jolla Institute for Immunology are also both developing pan-coronaviru­s vaccines that could transform the body’s immune response to the virus’s ever-changing mutations and protect people from new COVID-19 variants as well as even future coronaviru­ses.

As this illustrate­s, San Diego is one of the hubs of the nation’s life science ecosystem. That fact is also supported by the return this month — for the fourth time in 21 years — of BIO Internatio­nal Convention, one of the largest global events in biotech. BIO 2022 will draw thousands of scientists, entreprene­urs, researcher­s and journalist­s from around the world and across the life science landscape to discuss the future of the industry and the ways biotech improves our world and our quality of life.

Attendees will find themselves in a city whose life science community extends across research and manufactur­ing, medical devices and equipment, and traditiona­l biopharma drug developmen­t. Biotech is booming in our region, and it shows no signs of slowing down. According to a recent Biocom California report, San Diego County’s life science industry generated almost $28 billion in gross regional product and employed more than 72,000 people in 2020 — serving as one of the most significan­t economic drivers in the region. San Diego also received nearly $1.2 billion in funding from the National Institutes of Health, helping fuel research efforts in the region.

Countless academic and research institutio­ns, companies and organizati­ons working on life sciences and biotechnol­ogy are woven into the city’s fabric, and the industry prospers because San Diego maintains a collaborat­ive and intensely cooperativ­e business culture. Elected officials support our industry through smart policy making, while a steady flow of venture capital funding and a strong local talent pool ensure that companies of all shapes and sizes can thrive.

With early discovery and decisive actions, society can limit the spread of the next new virus, as it did with SARS-CoV in 2002, H1N1 in 2009 and MERS-CoV in 2012. We have no doubt that San Diego’s life science ecosystem will be at the center of these future efforts. In the meantime, the region will continue its groundbrea­king work in shaping the future of human health around the globe.

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