Los Angeles Times

Musk venture sets ambitious goals for implants in humans

- By Ashlee Vance Vance writes for Bloomberg.

Neuralink has yet to achieve its primary goal of implanting a computing device into the brain of a human. And yet, in typical fashion for an Elon Musk venture, the company is already bounding ahead, aiming implants at other body parts.

At an event Wednesday night at the company’s headquarte­rs in Fremont, Calif., Musk revealed work on two major products in addition to the brain-computer interface, which would need to be drilled into a person’s skull and would initially be used to treat traumatic brain injuries.

Neuralink is also developing implants that can go into the spinal cord and potentiall­y restore movement in someone suffering paralysis. And the company has an ocular implant meant to improve or restore human vision.

“As miraculous as that may sound, we are confident that it is possible to restore full-body functional­ity to someone who has a severed spinal cord,” Musk said at the event. Turning to Neuralink’s vision work, he said, “Even if they have never seen before, we are confident they could see.”

In parallel, Neuralink has been refining the main product for the brain, which consists of a tiny device and electrode-laced wires, along with a robot that carves out a piece of a person’s skull and implants the wiring. Ongoing discussion­s with the U.S. Food and Drug Administra­tion have gone well enough for the company to set a target of its first human trials within the next six months, Musk said.

The goal of the braincompu­ter interface, known as a BCI, is initially to allow a person with a debilitati­ng condition — such as amyotrophi­c lateral sclerosis, or ALS, or the aftereffec­ts of a stroke — to communicat­e via their thoughts. The company demonstrat­ed that with a monkey “telepathic­ally typing” on a screen in front of it.

The Neuralink device translates neuronal spikes into data that can be interprete­d by a computer. Musk’s hope is that the device could one day become mainstream and allow the transfer of informatio­n between humans and machines. He has long argued that humans can keep up with the advances being made by artificial intelligen­ce only with the help of computer-like augmentati­ons.

“You are so used to being a de-facto cyborg,” Musk said. “But if you’re interactin­g with your phone, you’re limited.”

As has been the case with previous Neuralink events, some of the things demonstrat­ed by Musk and his team have already been accomplish­ed in academic settings. The company’s critics have long accused Musk of over-hyping Neuralink’s advances and over-promising what the technology will be able to do in the near future, if ever.

Brain-machine interface technology has been researched and advanced by academia for decades. Musk’s entry into the arena, however, has spurred a wave of investment from venture capitalist­s in startups and helped push the field forward at a much more rapid clip.

A couple of similar startups are ahead of Neuralink when it comes to human trials. Synchron, for example, has been able to implant a small stent-like device into the brains of patients in Australia and the U.S. The product has made it possible for patients who were unable to move or speak to communicat­e wirelessly via computers and their thoughts. Onward Inc. has also done breakthrou­gh work restoring some movement in people with spinal cord injuries.

The type of brain surgery proposed by Neuralink is far more invasive than that of Synchron or most other competitor­s in the industry. A patient must have a chunk of their skull removed and allow wires to be implanted into their brain tissue. Neuralink has been doing tests for years on primates to prove that the surgery is safe and that the implant can remain inside the brain for long periods without causing harm.

Animal rights groups had criticized the primates’ treatment when Neuralink relied on a partner laboratory for some experiment­s. Neuralink has since brought its animal husbandry program in-house.

Neuralink’s advantage over its rivals is one of processing power. Musk’s bet is that the more invasive surgery, coupled with greater computing capabiliti­es, will help Neuralink’s hardware achieve better results and restore more functions in humans than competing products.

Musk’s company has already missed some of the billionair­e’s ambitious timelines for placing the BCI implant in people. In meetings with his team over the last several months, Musk urged his engineers in blunt terms to work faster and harder.

“We will all be dead before something useful happens,” Musk told his team during a recent product review meeting. “We need to step it up. We need to ship useful products.” During the same meeting, Musk expressed fear that advances in AI would outpace the work being done at Neuralink, rendering the company’s efforts worthless.

Some of Neuralink’s main concerns with the BCI implant have been making sure that the robot can perform surgeries quickly and with minimal harm to the body. Musk foresees a day when people get brain implants as a quick outpatient procedure.

The paralysis and ocular work began relatively recently, and Musk has been pressing his teams to advance the technology quickly.

Autumn Sorrells, the animal care director at Neuralink, has been working to make sure that the experiment­s done on the primates and pigs are conducted in a safe manner. Neuralink has an enclosure for the primates in Fremont that includes toys and television­s to keep the animals entertaine­d as people check to see how their implants are functionin­g.

Previously, the animals had to leave their cages and be restrained to have their implants recharged. More recently, Neuralink devised a setup that lets the primates recharge under a helmet in their cages while they eat. The company is building out a much more expansive animal enclosure at a campus in Austin, Texas.

Although still very much in its early days, the totality of work being done by Neuralink makes it the only general-purpose BCI company. Other startups have focused on the brain or the eye or the spinal cord. Meanwhile, Neuralink hopes to do it all.

 ?? Aaron Favila Associated Press ?? ELON MUSK said that in addition to work on placing a computing device in a human brain, his Neuralink venture is developing implants to restore movement in paralyzed people. Above, he talks virtually in Indonesia.
Aaron Favila Associated Press ELON MUSK said that in addition to work on placing a computing device in a human brain, his Neuralink venture is developing implants to restore movement in paralyzed people. Above, he talks virtually in Indonesia.

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