Los Angeles Times

The dark history of a Russian nerve agent

Germany says Putin opponent Alexei Navalny was poisoned with the Soviet-era toxin Novichok.

- By Laura King

The Russian name, in translatio­n, sounds innocuous, even jaunty: “newcomer,” “novice” or “new boy.” But the Soviet-developed family of advanced nerve agents collective­ly known as Novichok is among the deadliest substances created by humankind.

The German government on Wednesday announced “unequivoca­l” proof that hospitaliz­ed Russian anti-corruption crusader Alexei Navalny, who fell gravely ill Aug. 20 while aboard a domestic flight, was poisoned by a militarygr­ade agent from the banned Novichok group.

Nearly two weeks after being stricken, Navalny, 44, remains in a medically induced coma, his condition described as stable. Amid an internatio­nal outcry, he was brought to Berlin two days after his hospitaliz­ation in Siberia. Russian doctors who initially treated him denied any sign of poisoning, suggesting — ludicrousl­y, critics said — a metabolic disorder such as low blood sugar.

The German government’s conclusion, based on toxicology tests conducted by a specialize­d military laboratory, heightened already intense suspicions that the Kremlin was behind the attack on one of President Vladimir Putin’s most prominent critics, because of Novichok’s state origins, distinct toxicologi­cal footprint and the difficulty of making it.

Armed with medical proof of the sophistica­ted nerve agent’s use, Germany demanded an explanatio­n. Putin’s government, which has previously scoffed at the notion it played any role in Navalny’s collapse, responded with trademark nonchalanc­e.

Novichok was last in the headlines in 2018, when it was identified as the poison used against turncoat Russian spy Sergei Skripal in an assassinat­ion attempt attributed to Russian intelligen­ce agents. He and daughter Yulia, who was visiting him at his home in the quiet English town of Salisbury at the time of the attack, nearly died, but both eventually recovered.

The substance’s extreme lethality was evident more than three months after the attack when a British man who was scavenging trash found what looked like a discarded perfume bottle and gave it to his companion, Dawn Sturgess. She died soon after. British authoritie­s later concluded the counterfei­t perfume container had been used by Skripal’s attackers to transport the nerve agent.

Here is a look back at how Novichok came into existence.

How was it developed?

This class of organophos­phate nerve agents was the fruit of a Cold War-era effort by the then-Soviet Union to develop chemical weapons. Operating under the code name Foliant, the program created a number of Novichok variants, continuing into the early 1990s. Russian scientist Vil Mirzayanov, who disclosed the program’s existence before he defected to the West, wrote a 2008 book about secret Sovietera chemical weapons experiment­ation. Now 85 and living in the United States, he has freely voiced his suspicions about Novichok’s continuing use.

Russia has said the developmen­t of Novichok was halted by 1992, a year after the breakup of the Soviet Union. In 1997, Moscow joined the Chemical Weapons Convention, which last year put Novichok on its list of controlled substances, in effect banning it.

What are its effects on humans?

They are agonizing, by all accounts. Novichok is part of a class of cholineste­rase inhibitors, which prevent nerves from giving “messages” to muscles, triggering a cascade of collapse of bodily functions. Early signs of exposure include constricte­d pupils and ringing ears, followed by convulsion­s, vomiting and difficulty breathing as the lungs fill with fluid. It can be treated with antidotes including atropine, which impede its course but cannot fully counter the effects.

Several Novichok variants are far more toxic and powerful than the deadly VX nerve agent, which was believed to have been used by the North Korean government in 2017 to kill the halfbrothe­r of North Korean dictator Kim Jong Un.

Soviet scientists got a grisly glimpse of the effects when one of Novichok’s developers, Andrei Zheleznyak­ov, was accidental­ly exposed to residue in a laboratory mishap in 1987. He survived, but suffered debilitati­ng ailments that were thought to have directly contribute­d to his death five years later. “It’s got me,” he was said to have told lab colleagues at the time.

What do Navalny’s allies say?

At the time he was stricken, Navalny’s associates were quick to label his sudden illness a poisoning, voicing explicit public suspicions that Putin was behind the episode. Together with the dissident’s wife, they lobbied to have him flown to Germany for treatment, denouncing the delay as not only a threat to his life, but also an attempt to cover up the cause.

On Wednesday, after the German announceme­nt, a member of Navalny’s team, strategist Leonid Volkov, sardonical­ly likened the use of Novichok to a signed calling card left at the scene by the Russian leader, tweeting an image of a signature.

Novichok’s use is suspected in several domestic assassinat­ions in Russia. In Navalny’s case, associates say use of a substance so strongly associated with the state security services points to a brazen show of intimidati­on, rather than an attempt at stealth and secrecy.

What’s been the internatio­nal reaction?

Germany expressed outrage, and hopes to marshal allies’ support. At a news conference Wednesday, Chancellor Angela Merkel described Navalny as the victim of a crime.

“He was meant to be silenced,” she said of the dissident. “This raises very difficult questions that only the Russian government can answer — and must answer.”

As in previous such episodes, Moscow displayed elaborate bewilderme­nt. The Tass news agency quoted Kremlin spokesman Dmitry Peskov as saying that “informatio­n has not been relayed to us” about the scientists’ findings. Germany said it would formally convey the details via Russia’s embassy in Berlin.

The president of the European Commission, Ursula von der Leyen of Germany, said the attack was a “despicable and cowardly act” whose perpetrato­rs “need to be brought to justice.” In Britain, where there is still widespread outrage over the Skripal attack on its soil, Prime Minister Boris Johnson called the use of the toxin against Navalny “outrageous.”

The White House called the episode “reprehensi­ble,” but President Trump has been notably silent about the Navalny affair. Under his administra­tion, U.S.-German relations are cool, and it was unclear whether the United States would join in any diplomatic reprisals, as it did after the Skripal poisoning.

 ?? Alexander Zemlianich­enko Associated Press ?? EVIDENCE of Novichok in Russian Alexei Navalny, shown in 2019, heightens suspicions that the Kremlin was behind his poisoning, given the agent’s state origins, toxicologi­cal footprint and the difficulty of making it.
Alexander Zemlianich­enko Associated Press EVIDENCE of Novichok in Russian Alexei Navalny, shown in 2019, heightens suspicions that the Kremlin was behind his poisoning, given the agent’s state origins, toxicologi­cal footprint and the difficulty of making it.

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