First For Women

So simple, so effective

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Millions of women—and diet experts!—are supplement­ing with exogenous ketones to switch into fat-burning mode and jump-start slimming without experienci­ng the headaches, nausea and fatigue characteri­stic of ‘keto flu,’ says Dominic D’Agostino, Ph.D., an associate professor at the University of South Florida and the world’s leading exogenous ketone researcher. And while these ketones work in the short-term to offset hunger as your body switches from burning glucose to burning fat and stave off symptoms (which can linger for up to a month!), you can keep taking these supplement­s indefinite­ly, says exogenous ketone researcher Eric Plaisance, Ph.D., who does so himself.

“The higher your ketone levels, the more impressive your results will be,” says Plaisance. “And there are so many ways to use these supplement­s,” he says. You might take them for the first three weeks of a keto diet to help your body adjust to the switch from burning glucose to burning fats. You can also use them if you’re following a modified keto diet, where you’re consuming around 50 to 75 grams of carbohydra­tes a day. “In that range, you probably won’t produce a lot of ketones on your own,” says Plaisance, “so taking these supplement­s will enable you to boost your ketones.” They can also be used for long-term weight-loss maintenanc­e or as a short-term counter to high-carb “cheat” days, he adds.

Here’s how to incorporat­e them into your diet so you can find a strategy that works best for you.

Start here. There are three categories of exogenous ketones: keto fats like coconut oil and medium-chain triglyceri­des (aka MCT oil), ketone salts (which typically come in powder form) and ketone esters (liquid). Because esters tend to be bitter-tasting, many experts suggest opting for ketone salts and MCT oil or powder. “MCT oil combined with ketone salts work synergisti­cally to raise ketone levels and keep them elevated for hours,” D’Agostino explains. “This combinatio­n will give you better results than if you take ketone salts alone.” D’Agostino advises reading labels closely. “The ideal ketone supplement shouldn’t contain more than 2 grams of carbohydra­tes per serving, with less than 1 gram of sugar.” Two brands experts like: Simply GOODFATS Creamy MCT (SimplyGood­Fats.com) and KetoLogic BHB Exogenous Ketones (KetoLogic.com)

Take small steps. To avoid GI distress, gradually build up to 10 to 15 grams of exogenous ketones daily. “MCT oil can cause diarrhea, and some people report acid reflux after taking ketone esters,” says keto diet author Mary Newport, M.D., who recommends starting with 1⁄2 tsp. of MCT oil per day and increasing by

1⁄2 tsp. every few days. Same goes for ketone salts: Start with a quarter of the serving size and increase from there as you build tolerance. “This is especially important for diabetics who are on medication­s that lower blood glucose,” adds Dr. Newport. “Ketone supplement­s lower blood sugar so dramatical­ly that you can get into trouble, so err on the side of a low dose at first.”

Time it right. “When you take exogenous ketones depends on your goals,” says Dr. Plaisance, who adds that finding your optimal time of day to supplement may require some experiment­ation. “You might notice these supplement­s prevent you from getting hungry if you take them when fasting in the morning. Or you might try taking them after a higher-carb meal in an effort to blunt your bloodsugar response.” When you’re getting started, D’Agostino suggests spreading out the supplement­s so you get at least three doses a day, then clueing in to how you feel after taking them. “Personally, I find supplement­ing throughout the day very helpful when I’m sleep-deprived. Staying in ketosis gives me cognitive resilience under periods of sleep deprivatio­n if I’m not eating like I should. It’s a way to compensate if I’m not following through with other aspects of my life.”

Fill your plate with these

foods. To maximize the efficacy of exogenous ketone supplement­s, you’ll want to stick to a keto or low-carb plan, which will keep your insulin levels low and allow ketones to rise, says

Dr. Plaisance. Aim to fill at least onethird of your plate with non-starchy vegetables, like dark leafy greens, broccoli, cauliflowe­r, zucchini and asparagus. Another third should come from clean protein, like full-fat dairy, cagefree eggs, grass-fed meat and pasturerai­sed poultry. You’ll also want to eat plenty of ketone-promoting fats, such as olive oil, coconut oil, avocados, nuts, seeds and grass-fed butter.

Supplement on ‘cheat days’

Even if you cycle off using exogenous ketones, keep them on hand for cheat days. “When I travel or eat foods that take me out of ketosis, I’ll take a mix of MCT powder and ketone salts first thing every morning along with a big glass of water,” says D’Agostino. “This keeps me in ketosis.”

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