‘Smart bomb’ drug attacks breast cancer

Backers hope new treatment will be on market in a year.

the benefit becomes more clear with time. In fact, so many women on the new treatment are still alive that researchers cannot yet determine average survival for the group.

“The absolute difference is greater than one year in how long these people live,” said the study’s leader, Dr. Kimberly Blackwell of Duke University. “This is a major step forward.”

A warning to hopeful patients: the drug is still experimental, so not available yet. Its backers hope it can reach the market within a year.

The treatment builds on Herceptin, the first genetargeted therapy for breast cancer. It is used for about 20 percent of patients whose tumors overproduce a certain protein.

Researchers combined Herceptin with a chemotherapy so toxic that it can’t be given by itself, plus a chemical to keep the two linked until they reach a cancer cell where the poison can be released to kill it.

This double weapon, called T-DM1, is the “smart bomb,” although it’s actually not all that smart — Herceptin isn’t a homing device, just a substance that binds to breast cancer cells once it encounters them.

Richard LOS ANGELES — Dawson, the wisecracking British entertainer who was among the schemers in the 1960s sitcom “Hogan’s Heroes” and a decade later began kissing thousands of female contestants as host of the game show “Family Feud” has died. He was 79.

Dawson, also known to TV fans as the Cockney POW Cpl. Peter Newkirk on “Hogan’s Heroes,” died Saturday night from complications related to esophageal cancer at Ronald Reagan Memorial hospital, his son Gary said.

The game show, which initially ran from 1976 to 1985, pitted families who tried to guess the most popular answers to poll questions such as “What do people give up when they go on a diet?”

Dawson won a daytime Emmy Award in 1978 as best game show host. Tom Shales of The Washington Post called him “the fastest, brightest and most beguilingly caustic interlocutor since the late great Groucho bantered and parried on ‘You Bet Your Life.’” The show was so popular it was released as both daytime and syndicated