Baltimore Sun Sunday

Zoo preparing to vaccinate otters, chimps, lions, more

- By Christine Condon

The big cats at the Maryland Zoo in Baltimore will be among the first in line.

They’ll saunter over to the edge of their enclosure, likely lured by a piece of ground meat, and present one of their hips to a waiting zookeeper, who will inject them with a specially made COVID-19 vaccine.

When all is said and done, they might even receive a “jackpot” prize, like flank steak, said associate veterinari­an Dr. John Flanders.

In the next few months, the zoo will begin administer­ing two-dose vaccines to 30 of its animals, Flanders said — from North American river otters to Amur leopards. Not all will be as easily persuaded as the felines.

“We’ve really focused a lot of effort on just minimizing risk and transmissi­on as best as possible,” Flanders said. “And now, this vaccine is hopefully going to be another tool for us to help us minimize risk if these animals get exposed.”

The vaccines will be donated by a company called Zoetis, which is providing 11,000 free doses of its COVID-19 vaccine to mammals living in 70 zoos and animal care facilities.

The company’s vaccine doesn’t use mRNA, like the Pfizer BioNTech and Moderna shots, or a viral vector, like the Johnson & Johnson vaccine. Instead, it uses synthetic spike protein made from that of SARSCoV-2.

The zoo doesn’t have any vaccines in hand yet, but a shipment is expected in a few weeks to a month, said Jane Ballentine, a spokespers­on for the zoo.

First will come the lions, leopards, bobcats and cheetahs, and the zoo’s American badger — high-risk animals who have been trained to receive injections in a cooperativ­e manner. Vulnerable but less amenable species, including the zoo’s great apes and chimpanzee­s, will be in the second tier for vaccinatio­n. Some of those animals may need to be anesthetiz­ed to receive their shots.

“We anticipate they’re not all going to comply, or they might have a bad day that day,” Flanders said. “It just depends on their mood.”

Afterward, those primates might receive a particular­ly desirable piece of fruit, Flanders said.

The third and final tier will include lower-risk animals, such as lemurs. No COVID19 cases have been discovered in that species, but experts worry that their membership in the primate family may make them susceptibl­e to the virus.

The main is worry is that human keepers could transmit COVID-19 to animals unwittingl­y. At the Maryland Zoo, keepers and other staff have been donning masks and face shields to care for the animals since the pandemic began, Flanders said.

Although zoo animals are unlikely to be exposed to the virus via patrons, they come in fairly close contact with any number of veterinari­ans, maintenanc­e workers and keepers throughout their lives, Flanders said, who all could expose them to COVID-19.

Some animals at the Maryland Zoo have been tested for COVID-19, Flanders said, but all have come back negative.

Another worry is that the virus, once inside an animal, could mutate, creating new variants for humans to contend with, said Xiaoping Zhu, chair of the University of Maryland’s Department of Veterinary Medicine.

Long term, Zhu said officials should consider recommendi­ng COVID19 vaccinatio­ns for more animals.

In the meantime, the world’s focus is still trained on vaccinatin­g as many people as possible. Globally, roughly one-third of people are fully vaccinated, according to Our World in Data.

In the United States, 53.9% of people have been fully vaccinated, according to the

Centers for Disease Control and Prevention.

But efforts to immunize animals don’t detract from that all-important aim, Flanders said.

“It’s not a human product.,” he said. “We’re not taking any human doses out of the circulatio­n.

“And it’s manufactur­ed by a veterinary company, so it’s not that they are taking manufactur­ing away from human vaccine doses. This is completely separate.”

So far, the U.S. Department of Agricultur­e has confirmed 231 cases of COVID-19 in animals not on farms.

There have been a series of damaging outbreaks on mink farms. In June, Oregon’s Department of Agricultur­e required mink ranchers to vaccinate their animals against the virus.

The most cases have been reported are among domestic dogs and cats, followed by tigers, otters, gorillas, lions, snow leopards and cougars.

The World Small Animal Veterinary Associatio­n has yet to recommend household animals receive the vaccine, particular­ly because the CDC has said the risk of animals spreading the disease to humans is low. The USDA is approving animal COVID-19 vaccinatio­ns only on a caseby-case basis. The Maryland Zoo is also keeping state veterinari­ans apprised, Flanders said.

Many animals have fared well after their diagnoses, although, notably, two lions died of COVID-19 at a zoo in India earlier this summer amid that country’s spike in cases tied to the delta variant. And Danish officials ordered millions of minks slaughtere­d after outbreaks at hundreds of farms there.

“Minks have been shown to be very susceptibl­e to this, and it kind of runs rampant throughout their population­s,” Flanders said. “I certainly do not want to even begin to think about that happening to one of our animal population­s here.”

 ?? BARBARA HADDOCK TAYLOR/BALTIMORE SUN ?? Emma Wenzel of Baltimore interacts with Louie the chimp at the Maryland Zoo in March.
BARBARA HADDOCK TAYLOR/BALTIMORE SUN Emma Wenzel of Baltimore interacts with Louie the chimp at the Maryland Zoo in March.

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